American Society for Microbiology, Journal of Clinical Microbiology, 2(47), p. 466-468, 2009
DOI: 10.1128/jcm.00892-08
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ABSTRACT No mutations were detected in the hemagglutinin gene of influenza A/H3N2 virus isolates from patients undergoing short-term amantadine treatment. However, genetic changes occurred after serial passage in either MDCK or MDCK-SIAT1 cells. Our results showed that only a few mutations were observed in MDCK-SIAT1-passaged isolates in the presence of amantadine.